1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

This essay considers what it means to understand natural language and whether a computer running an artificial-intelligence program designed to understand natural language does in fact do so. It is argued that a certain kind of semantics is needed to understand natural language, that this kind of semantics is mere symbol manipulation (i.e., syntax), and that, hence, it is available to AI systems. Recent arguments by Searle and Dretske to the effect that computers cannot understand natural language are discussed, and (...) a prototype natural-language-understanding system is presented as an illustration. (shrink)

John Searle once said: "The Chinese room shows what we knew all along: syntax by itself is not sufficient for semantics. (Does anyone actually deny this point, I mean straight out? Is anyone actually willing to say, straight out, that they think that syntax, in the sense of formal symbols, is really the same as semantic content, in the sense of meanings, thought contents, understanding, etc.?)." I say: "Yes". Stuart C. Shapiro has said: "Does that make any sense? Yes: Everything (...) makes sense. The question is: What sense does it make?" This essay explores what sense it makes to say that syntax by itself is sufficient for semantics. (shrink)

Canonically, ‘classic’ tests of general relativity (GR) include perihelion precession, the bending of light around stars, and gravitational redshift; ‘modern’ tests have to do with, _inter alia_, relativistic time delay, equivalence principle tests, gravitational lensing, strong field gravity, and gravitational waves. The orthodoxy is that both classic and modern tests of GR afford experimental confirmation of that theory _in particular_. In this article, we question this orthodoxy, by showing there are classes of both relativistic theories (with spatiotemporal geometrical properties different (...) from those of GR) and non-relativistic theories (in which the lightcones of a relativistic spacetime are ‘widened’) which would also pass such tests. Thus, (a) issues of underdetermination in the context of GR loom much larger than one might have thought, and (b) given this, one has to think more carefully about what exactly such tests in fact _are_ testing. (shrink)

The proper treatment of computationalism, as the thesis that cognition is computable, is presented and defended. Some arguments of James H. Fetzer against computationalism are examined and found wanting, and his positive theory of minds as semiotic systems is shown to be consistent with computationalism. An objection is raised to an argument of Selmer Bringsjord against one strand of computationalism, namely, that Turing-Test± passing artifacts are persons, it is argued that, whether or not this objection holds, such artifacts will inevitably (...) be persons. (shrink)

An outline is given of the proof that the consistency of a κ⁺-Mahlo cardinal implies that of the statement that I[ω₂] does not include any stationary subsets of Cof(ω₁). An additional discussion of the techniques of this proof includes their use to obtain a model with no ω₂-Aronszajn tree and to add an ω₂-Souslin tree with finite conditions.

There are many branches of philosophy called “the philosophy of X,” where X = disciplines ranging from history to physics. The philosophy of artificial intelligence has a long history, and there are many courses and texts with that title. Surprisingly, the philosophy of computer science is not nearly as well-developed. This article proposes topics that might constitute the philosophy of computer science and describes a course covering those topics, along with suggested readings and assignments.

Hauser argues that his pocket calculator (Cal) has certain arithmetical abilities: it seems Cal calculates. That calculating is thinking seems equally untendentious. Yet these two claims together provide premises for a seemingly valid syllogism whose conclusion - Cal thinks - most would deny. He considers several ways to avoid this conclusion, and finds them mostly wanting. Either we ourselves can't be said to think or calculate if our calculation-like performances are judged by the standards proposed to rule out Cal; or (...) the standards- e.g., autonomy and self-consciousness- make it impossible to verify whether anything or anyone (save oneself) meets them. While appeals to the intentionality of thought or the unity of minds provide more credible lines of resistance, available accounts of intentionality and mental unity are insufficiently clear and warranted to provide very substantial arguments against Cal's title to be called a thinking thing. Indeed, considerations favoring granting that title are more formidable than is generally appreciated. Rapaport's comments suggest that, on a strong view of thinking, mere calculating is not thinking (and pocket calculators don't think), but on a weak, but unexciting, sense of thinking, pocket calculators do think. He closes with some observations on the implications of this conclusion. (shrink)

A critical survey of some attempts to define ‘computer’, beginning with some informal ones, then critically evaluating those of three philosophers, and concluding with an examination of whether the brain and the universe are computers.

This essay examines the role of non-existent objects in "epistemological ontology" — the study of the entities that make thinking possible. An earlier revision of Meinong's Theory of Objects is reviewed, Meinong's notions of Quasisein and Außersein are discussed, and a theory of Meinongian objects as "combinatorially possible" entities is presented.

This book is unified by three broad concerns: the rationality of belief in God, the relation between religion and morality, and the explication of the concept of God. The essays are, however, marked by diversity. Some focus on historical figures, such as Aquinas and Locke; others bring recent epistemological and metaphysical developments to bear on problems of religious belief. Some of the papers explore neglected issues central to religious practice, such as the question of how total devotion to God can (...) permit other deep commitments; others apply philosophical distinctions from within a religious tradition, for example, in setting out a Christian approach to the problem of evil. (shrink)

This article presents findings from a series of research studies designed to identify classroom teaching practices that can enhance moral reasoning of undergraduate students in business foundational courses. The research, conducted over five semesters at a Midwestern university, resulted in the development of teaching methods and materials that can, when properly sequenced and integrated into undergraduate business courses, increase levels of student moral reasoning as measured by the revised version of the Defining Issues Test (DIT-2). Findings in this research demonstrate (...) that faculty members who are not specialists in business ethics can effect positive increases in student moral reasoning in non-ethics business courses. However, significant time and effort must be invested in case-based moral decision making, and grade incentives for students to engage the use of an ethical decision-making framework are required. (shrink)

In this comment I discuss the role of an ethics case consultant in an institutional setting, in contrast to situations when an ethics consultant serves an individual client. In the former situation, I believe the case consultant should articulate ethical issues, options, and arguments, but not recommend a particular course of conduct. In the latter situation, the role of the ethics consultant can be defined and determined in negotiations with the client.

We believe that clinical ethics consultants (CECs) should offer advice, options, and recommendations to attending physicians and their teams. In their article in this issue of The Journal of Clinical Ethics, however, Kornfeld and Prager give CECs a somewhat different role. The CEC they describe may at times be more aptly understood as a medical interventionist who appropriates the roles of the attending physician and the medical team than as a traditional CEC. In these remarks, we distinguish the role of (...) the CEC from that of the physician, in contrast to some of these authors’ recommendations, which confuse the two roles. (shrink)

Alexius Meinong developed a notion of defective objects in order to account for various logical and psychological paradoxes. The notion is of historical interest, since it presages recent work on the logical paradoxes by Herzberger and Kripke. But it fails to do the job it was designed for. However, a technique implicit in Meinong's investigation is more successful and can be adapted to resolve a similar paradox discovered by Romane Clark in a revised version of Meinong's Theory of Objects due (...) to Rapaport. One family of paradoxes remains, but it is argued that they are unavoidable and relatively harmless. (shrink)

This essay describes computational semantic networks for a philosophical audience and surveys several approaches to semantic-network semantics. In particular, propositional semantic networks are discussed; it is argued that only a fully intensional, Meinongian semantics is appropriate for them; and several Meinongian systems are presented.

Despite widespread agreement that we have moral responsibilities to future generations, many are reluctant to frame the issues in terms of justice and rights.There are indeed philosophical challenges here, particularly concerning nonoverlapping generations. They can, however, be met. For example, talk of justiceand rights for future generations in connection with climate change is both appropriate and important, although it requires revising some common theoreticalassumptions about the nature of justice and rights. We can, in fact, be bound by the rights of (...) future people, despite the “non-identity problem,” and the force of these rights cannot be diluted by “discounting” future costs. Moreover, a rights-based approach provides an effective answer to political arguments against taking mandatory measures to curb greenhouse gas emissions when these are unpopular with a democratic populace. (shrink)

This essay is a rudimentary effort at the functional specialization of dialectic. Following Lonergan’s maxim in Insight to develop positions and to reverse counterpositions, it takes a relatively simple puzzle about eisegesis and criticises some basic confusions about what goes “into” the reading of texts. In the process two counterpositions on the meaning of “text” are criticised and an alternative to both defended.

The claim that glycogen contains protein was first made exactly 100 years ago and has been the subject of contention ever since. It has now been established that rabbit‐muscle glycogen contains a covalently bound protein of Mr 37,000, present in equimolar proportion to glycogen. The protein, named glycogenin, is joined to muscle glycogen via a novel linkage involving the hydroxyl group of tyrosine, a fact of possible significance in the light of insulin's message being transmitted by tyrosine phosphorylation. The protein (...) is seen as the biogenetic precursor of glycogen. Its existence suggests an additional mode of regulation of glycogen metabolism since the amount, turnover and cellular location of glycogenin will influence the corresponding parameters for glycogen. A protein “primer” is suggested for the biogenesis of storage polysaccharides in general. (shrink)

Book reviewed in this article: Madness and the Criminal Law. By Norval Morris. The Insanity Plea: The Uses and Abuses of the Insanity Defense. By William J. Winslade and Judith Wilson Ross.

In the movieRegarding Henry, the main character, Henry Turner, is a lawyer who suffers brain damage as a result of being shot during a robbery. Before being wounded, the Old Henry Turner had been a successful lawyer, admired as a fierce competitor and well-known for his killer instinct. As a result of the injury to his brain, the New Henry Turner loses the personality traits that had made the Old Henry such a formidable adversary.

Este ensaio examina o relacionamento possível entre o pensamento de Martin Heidegger enquanto emerge no Zollikon Seminaire na sua troca de idéias com Medard Boss e a perspectiva da psicanálise como aparece através do prisma da releitura de Freud oferecido por Jacques Lacan. Heidegger entende Freud como vítima de uma compreensão positivista da ciência que procura explicar o comportamento humano patológico por um complexo de causas discerníveis conscientemente. Quando determinados fenômenos não podem ser explicados desta maneira, Freud postula um jogo (...) de causas psíquicas que não são conscientes, cuja soma ele chama o "inconsciente". Desde que todos os fenômenos humanos são, para Heidegger, discerníveis via uma profunda fenomenologia do ser humano como o ser-no-mundo, a construção hipotética de Freud é desnecessária e, a longo prazo, perniciosa. Mas Lacan propõe uma nova maneira de compreender o inconsciente descoberto por Freud, a saber, que não deve ser entendido como um sistema físico de forças hidráulicas, mas como um processo que seja estruturado como um idioma. A pergunta levantada neste ensaio é se Heidegger seria ou não igualmente hostil à hipótese de Freud, apresentada a ele dentro da forma de Lacan, como algo "estruturado como um idioma". O ensaio sugere que a resposta poderia ser "provavelmente não". Baseado num exemplo clínico altamente simplificado, este ensaio esforça-se para mostrar a compatibilidade entre determinados conceitos básicos de Heidegger e diversos, de Lacan, em especial as noções da verdade e da liberdade.This paper examines the possible relationship between the thought of Martin Heidegger as it emerges in the Zollikon Seminaire through his exchange with Medard Boss and the perspective of psychoanalysis as it appears through the prism of Jacques Lacan's rereading of Freud. Heidegger takes Freud to be victim of a positivist conception of science that seeks to explain pathological human behaviour by a complex of consciously discernible causes. When certain phenomena cannot be explained in this way, Freud postulates a set of psychic causes that are not conscious, the sum total of which he calls the "unconscious." Since all human phenomena are, for Heidegger, discernible through a thorough-going phenomenology of human being as being-in-the-world, Freud's hypothetical construct is unnecessary and, in the long run, pernicious. But Lacan proposes a new way to understand the unconscious that Freud discovered, namely, that it is not to be thought of as analogous to a physical system of hydraulic forces but rather to a process that is structured like a language. The question raised in the paper is whether or not Heidegger would have been equally hostile to Freud's hypothesis, if it had been presented to him in Lacanian fashion as something "structured like a language". The paper suggests that the answer could be "probably not". On the basis of a highly simplified clinical example, it endeavors to show the compatibility between certain basic Heideggerean concepts and several of those essential to Lacan, especially the notions of truth and freedom. (shrink)

Book reviewed in this article: In Search of History: Historiography in the Ancient World and the Origins of Biblical History. By John Van Seters. The Hidden God: The Hiding of the Face of God in the Old Testament. By Samuel E. Balentine. Theodicy in the Old Testament. Edited by James L. Crenshaw. Ce Dieu censé aimer la Souffrance. By François Varone. Evil and Evolution, A Theodicy. By Richard W. Kropf. ‘Poet and Peasant’ and ‘Through Peasant Eyes’: A Literary‐Cultural Approach to (...) the Parable in Luke. By Kenneth Bailey. The Biblical Foundations for Mission. By Donald Senior and Carroll Stuhlmueller. New Testament Foundations of Ministry. By Colin Kruse. Church, Ministry and Unity. By James E. Griffiss. Theology of Ministry. By Thomas Franklin O'Meara. Yesterday and Today: A Study of Continuities in Christology. By Colin E. Gunton. I believe in the Holy Spirit. By Yves Congar. Between Jesus and Paul. By Martin Hengel. From Nicaea to Chalcedon: A Guide to the Literature and its Background. By Frances Young. Alan of Lille: The Frontiers of Theology in the Later Twelfth Century. By G.R. Evans. Mystic and Pilgrim: The Book and the World of Margery Kempe. By Clarissa W. Atkinson. Church, Politics and Society: Scotland 1408–1929. Edited by N. Macdougall. Renaissance and Reform: The Italian Contribution. Collected Essays, Volume II. By Frances A. Yates. Seven‐Headed Luther: Essays in Commemoration of a Quincentury, 1483–1983. Edited by Peter Newman Brooks. Ökumenische Erschliessung Martin Luthers. Edited by Peter Manns and Harding Meyer. Luther's Ecumenical Significance, An Interconfessional Consultation. Edited by Peter Manns and Harding Meyer, in collaboration with Carter Lindberg and Harry McSorley. States of Mind: A Study of Anglo‐Irish Conflict 1780 to 1980. By Oliver MacDonagh. The Parish Clergy in Nineteenth‐Century Russia: Crisis, Reform, Counter Reform. By Gregory L. Freeze. Pusey Rediscovered. Edited by Perry Butler. Between Two Worlds: George Tyrrell's Relationship to the Thought of Matthew Arnold. By Nicholas Sagovsky. The Concept of Glaubenslehre. By Walter E. Wyman, Jr. The Existence and Nature of God. Edited by Alfred J. Freddoso. Faith and Reason. By Anthony Kenny. Logic and The Nature of God. By Stephen T. Davis. Personal Responsibility and Christian Morality. By Josef Fuchs. Morality and Conflict. By Stuart Hampshire. Realism and Imagination in Ethics. By Sabina Lovibond. Intentionality. By John R. Searle. Philosophical Papers, I: Practical Reason. By G.H. von Wright. Philosophical Papers, II: Philosophical Logic. By G.H. von Wright. A Model of Making: Literary Criticism and its Theology. By Ruth Etchells. The Return of the Goddess: Femininity, Aggression and the Modern Grail Quest. By Edward Whitmont. The Power of the Poor in History. By Gustavo Gutierrez, translated by Robert R. Barr. The God of the Xhosa. By Janet Hodgson. Our Hymn Tunes: Their Choice and Performance. By Donald Webster. The Almighty Wall: The Architecture of Henry Vaughan. By William Morgan. An Introduction to Plato's Laws. By R.E. Stalley. Plato's Late Ontology: A Riddle Resolved. By Kenneth M. Sayre. Plato's ‘Parmenides’: Translation and Analysis. By R.E. Allen. Politics in the Ancient World. By M.I. Finley. (shrink)

Part I argues that ontological arguments, like other classical proofs of the existence of God, are parts of larger arguments in which they are embedded. These larger arguments include reasons supporting the proofs’ premises and responses to them, and to the proofs’ claims to validity and non-circularity, since, in the final analysis, our assessment of the proofs will express our best judgment of the cumulative force of all the considerations bearing on their overall adequacy. Part II illustrates these points by (...) examining contemporary defences of, and attacks on, one of the ontological argument’s central premises, namely, that God’s existence is logically possible. (shrink)

This volume by William J. Webb explores the hermeneutical maze that accompanies any treatment of these three controversial topics and takes a new step toward breaking down walls within the evangelical community related to them.

The differentiation of mammalian neurons during development is a highly complex process involving regulation and coordination of gene expression at multiple steps. The P19 mouse embryonal carcinoma cell line is a suitable model system with which to analyze regulation of neuronal differentiation. These multipotential cells can be maintained and propagated in tissue culture in an undifferentiated state. Exposure of aggregated P19 cells to retinoic acid results in the differentiation of cells with many fundamental phenotypes of mammalian neurons. Undifferentiated P19 cells (...) are amenable to genetic manipulations such as transfection and establishment of stable clonal cell lines expressing introduced genes. Proteins that play a key role in the neuronal differentiation of P19 cells are beginning to be identified. These include retinoic acid receptors, the epidermal growth factor receptor and the transcription factors Oct‐3 and Brn‐2. The biological and technical advantages of this system should facilitate deeper analysis of the activities of proteins that play a role in neuronal differentiation. (shrink)